GM@mTG-V microspheres promote NP regeneration by reconstructing IVD biomechanics and inflammatory microenvironment

GM@mTG-V microspheres promote NP regeneration by reconstructing IVD biomechanics and inflammatory microenvironment

Intervertebral disc degeneration (IVDD) has emerged as a significant global public health challenge, imposing substantial burdens on both individuals and society. Growing evidence suggests that modulating the mechanical microenvironment and alleviating inflammation in degenerated IVDs can promote ti...

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Bibliographic Details
Main Authors: Rong Gao, Yongfeng Zhang, Bo Deng, Jiawei Zhang, Zhuowen Liang, Zhao Wei, Feng Xu, Tan Ding
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
Subjects:
Intervertebral disc degeneration (IVDD)
Mechanical microenvironment
Vanillin
Extracellular matrix (ECM)
Inflammatory response
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425004570
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