Targeting MCH Neuroendocrine Circuit in Lateral Hypothalamus to Protect Against Skeletal Senescence

Targeting MCH Neuroendocrine Circuit in Lateral Hypothalamus to Protect Against Skeletal Senescence

Abstract Neuroendocrine regulation is essential for maintaining metabolic homeostasis. However, whether neuroendocrine pathway influence bone metabolism and skeletal senescence is unelucidated. Here, a central neuroendocrine circuit is identified that directly controls osteogenesis. Using virus base...

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Bibliographic Details
Main Authors: Bin Guo, Yong Zhu, Shuai Lu, Xiangming Chen, Zhuoqun Ren, Yuqi Liu, Hao Luo, Chao Wang, Xucheng Yang, Jianxi Zhu
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
BMSC
lateral hypothalamus
melanin concentrating hormone
neuroendocrinology
osteogenesis
skeletal senescence
Online Access:https://doi.org/10.1002/advs.202309951
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https://doi.org/10.1002/advs.202309951

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