Methylophiopogonanone A Inhibits Ferroptosis in H9c2 Cells: An Experimental and Molecular Simulation Study

Methylophiopogonanone A Inhibits Ferroptosis in H9c2 Cells: An Experimental and Molecular Simulation Study

In this study, homoisoflavone methylophiopogonanone A (MOA) was investigated for its inhibitory effect on ferroptosis of H9c2 cells using a set of cellular assays, such as BODIPY-probed and H<sub>2</sub>DCFDA-probed flow cytometry analyses, cell counting kit-8 analysis (CCK-8), and lacta...

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Bibliographic Details
Main Authors: Yanqing Wang, Xi Zhao, Ban Chen, Shaoman Chen, Yongbai Liang, Dongfeng Chen, Xican Li
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
homoisoflavone
ferroptotic inhibition
H9c2 cell line
molecular docking simulation
molecular dynamics simulation
Online Access:https://www.mdpi.com/1420-3049/29/23/5764
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