Attenuation of skin injury by a MARCO targeting PLGA nanoparticle

Attenuation of skin injury by a MARCO targeting PLGA nanoparticle

Abstract Cutaneous exposure to the DNA alkylating class of chemotherapeutic agents including nitrogen mustard (NM) leads to both skin injury and systemic inflammation. Circulating myeloid subsets recruited to the skin act to further exacerbate local tissue damage while interfering with the wound hea...

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Main Authors: Ummiye V. Onay, Dan Xu, Dauren Biyashev, Spencer T. Evans, Michael M. Demczuk, Tobias Neef, Joseph R. Podojil, Sara Beddow, Nathan C. Gianneschi, I. Caroline Le Poole, Stephen D. Miller, Kurt Q. Lu
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-024-00381-z
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https://doi.org/10.1038/s41536-024-00381-z

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