The efficacy and safety of first-line monotherapies in primary therapy of invasive aspergillosis: a systematic review

The efficacy and safety of first-line monotherapies in primary therapy of invasive aspergillosis: a systematic review

ObjectiveSeveral antifungals are available for the treatment of patients with invasive aspergillosis (IA). This study aims to evaluate the relative efficacy and safety of the first-line monotherapies in primary therapy of IA through network meta-analysis (NMA).MethodsWe systematically searched PubMe...

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Main Authors: Yan Chen, Jiaojiao Zhao, Yifei Wang, Long Ge, Joey Sum-wing Kwong, Junjie Lan, Rui Zhang, Huaye Zhao, Linfang Hu, Jiaxue Wang, Shuimei Sun, Songsong Tan, Xiaoqing Lin, Rui He, Wenyi Zheng, Xiaosi Li, Jiaxing Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
invasive aspergillosis
antifungals
network meta-analysis
aspergillus
posaconazole
amphotericin B deoxycholate
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1530999/full
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