Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity.

The human pathogens Plasmodium and Schistosoma are each responsible for over 200 million infections annually, especially in low- and middle-income countries. There is a pressing need for new drug targets for these diseases, driven by emergence of drug-resistance in Plasmodium and an overall dearth o...

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Bibliographic Details
Main Authors: Mukul Rawat, Gilda Padalino, Edem Adika, John Okombo, Tomas Yeo, Andrea Brancale, David A Fidock, Karl F Hoffmann, Marcus C S Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012216
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