Mutations in human cytymegalovirus (Orthoherpesviridae: Herpesvirales: Cytomegalovirus: Cytomegalovirus humanbeta 5) UL97 gene lead to increase in viremia duration and poor antiviral response in recipients of allogeneic hematopoietic stem cells

Mutations in human cytymegalovirus (Orthoherpesviridae: Herpesvirales: Cytomegalovirus: Cytomegalovirus humanbeta 5) UL97 gene lead to increase in viremia duration and poor antiviral response in recipients of allogeneic hematopoietic stem cells

Introduction. Human cytomegalovirus (Orthoherpesviridae: Herpesvirales: Cytomegalovirus: Cytomegalovirus humanbeta 5) (HCMV) is one of the most commonly detected viruses in recipients of allogeneic hematopoietic stem cell (allo-HSCT) transplants. However, the emergence of resistance to antiviral dru...

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Main Authors: Dmitriy S. Tikhomirov, Mikhail V. Demin, Anastasia A. Serikova, Bella V. Biderman, Andrey B. Sudarikov, Felix P. Filatov, Tatiana A. Tupoleva
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2024-11-01
Series:Вопросы вирусологии
Subjects:
human cytomegalovirus (hcmv)
hematopoietic stem cells (hscs) transplantation
viral chemoresistance
ganciclovir (gcv)
antiviral therapy
Online Access:https://virusjour.crie.ru/jour/article/viewFile/16670/926
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