Unraveling the role of the WIPF1/ACTN4 complex in podosome formation of human placental EVTs: Insights into recurrent spontaneous abortion

Unraveling the role of the WIPF1/ACTN4 complex in podosome formation of human placental EVTs: Insights into recurrent spontaneous abortion

Successful placental development and pregnancy rely on effective extravillous trophoblast (EVT) invasion. The mechanisms underlying inadequate EVT invasion in recurrent spontaneous abortion (RSA) remain unclear. WAS/WASL interacting protein family member 1 (WIPF1), the key regulator of cytoskeletal...

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Bibliographic Details
Main Authors: Cong Li, Shengya Wang, Jing Tang, Xin Luo, Luxing Ge, Youlong Xie, Lijuan Fu, Lingling Ruan, Enoch Appiah Adu-Gyamfi, Fangfang Li, Yingxiong Wang, Hongbo Qi, Yubin Ding
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-11-01
Series:Genes and Diseases
Subjects:
Extravillous trophoblasts
Invasion
Podosome formation
Recurrentspontaneous abortion
WIPF1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304225001540
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