Identification of disulfidptosis-related prognostic biomarkers associated with CD4 + and CD8 + T cells infiltration for sarcoma by integrating bioinformatic analysis and experimental validation

Identification of disulfidptosis-related prognostic biomarkers associated with CD4 + and CD8 + T cells infiltration for sarcoma by integrating bioinformatic analysis and experimental validation

Abstract Recently identified, disulfidptosis represents a novel form of cell death triggered by disulfide stress. The impact of disulfidptosis-related gene (DRG) patterns on the clinical prognosis of sarcoma, however, remains unexplored. In this study, two prognostic genes related to DRGs, CCDC69 an...

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Bibliographic Details
Main Authors: Wenliang Tan, Xi Zhou, Ting Wang, Shuanghua Wu, Ting Mo, Zhiqin Xie, Yang Xie
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
Disulfidptosis
Sarcoma
Prognosis
CCDC69
HMGB3
Online Access:https://doi.org/10.1007/s12672-025-03127-5
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