Protocol for generation of PD-modeling-induced neurons and detection of α-synuclein forms

Summary: Alpha-synuclein (α-Syn) is an important molecule in the pathogenesis of Parkinson’s and Alzheimer’s disease-related dementias such as Lewy body dementia, forming multiple pathological species. In vitro disease models, including human neurons and α-Syn-transfected cells, are instrumental to...

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Bibliographic Details
Main Authors: Francesco V. Nardi, Gulimiheranmu Maisumu, You Zhou, Bo Liang, Abraam M. Yakoub
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724006129
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