Machine learning based clinical decision tool to predict acute kidney injury and survival in therapeutic hypothermia treated neonates

Abstract Therapeutic hypothermia (TH) significantly reduces mortality and morbidities in neonates with Neonatal Encephalopathy (NE). NE may result in neonatal death and multisystem organ impairment, including acute kidney injury (AKI). Our study aimed to utilize machine learning (ML) methods to pred...

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Main Authors: Elif Keles, Syed Yaseen Ali, Pia Wintermark, Pieter Annaert, Floris Groenendaal, Suzan Şahin, Mehmet Yekta Öncel, Didem Armangil, Esin Koc, Malcolm R. Battin, Alistair J. Gunn, Adam Frymoyer, Valerie Chock, Djalila Mekahli, John van den Anker, Anne Smits, Karel Allegaert, Ulas Bagci
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-01141-9
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