Dilated cardiomyopathy and myocarditis: a clinical case
The article describes a clinical case of a combination of myocarditis and hereditary dilated cardiomyopathy. In a 40-year-old man cardiomegaly and HF, which occurred for the first time, were initially associated with an inflammatory process in the myocardium. Further genetic examinations showed that...
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| Format: | Article |
| Language: | English |
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TOV Chetverta Khvylia
2023-12-01
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| Series: | Кардіохірургія та інтервенційна кардіологія |
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| Online Access: | https://csic.com.ua/en/issues/archive/3-4-2023/1423-dilated-cardiomyopathy-and-myocarditis-a-clinical-case.html |
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| author | O.V. Onyshchenko D.V. Riabenko O.A. Yepanchintseva |
| author_facet | O.V. Onyshchenko D.V. Riabenko O.A. Yepanchintseva |
| author_sort | O.V. Onyshchenko |
| collection | DOAJ |
| description | The article describes a clinical case of a combination of myocarditis and hereditary dilated cardiomyopathy. In a 40-year-old man cardiomegaly and HF, which occurred for the first time, were initially associated with an inflammatory process in the myocardium. Further genetic examinations showed that pathological processes in the myocardium are also associated with a pathogenic mutation in the FLNC gene and a mutation in the TNT gene. The myocarditis that developed on the background of family (hereditary) dilated cardiomyopathy. However, despite the positive effect of the treatment of myocarditis and contemporary drug therapy, the progression of the pathological process in the myocardium was noted. This clinical case emphasizes the importance of a complete diagnostic examination with the use of genetic testing in certain cases.
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| format | Article |
| id | doaj-art-ed416455a522475f8189ca7704ddb58b |
| institution | Kabale University |
| issn | 2305-3127 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | TOV Chetverta Khvylia |
| record_format | Article |
| series | Кардіохірургія та інтервенційна кардіологія |
| spelling | doaj-art-ed416455a522475f8189ca7704ddb58b2025-01-17T15:59:21ZengTOV Chetverta KhvyliaКардіохірургія та інтервенційна кардіологія2305-31272023-12-013/4445210.31928/2305-3127-2023.3-4.4452Dilated cardiomyopathy and myocarditis: a clinical caseO.V. Onyshchenko0https://orcid.org/0009-0000-0676-0121D.V. Riabenko1https://orcid.org/0000-0002-4898-5342O.A. Yepanchintseva2https://orcid.org/0000-0001-7054-1564Heart Institute of the Ministry of Health of Ukraine, Kyiv, UkraineNational Scientific Center «M.D. Strazhesko Institute of Cardiology, Clinical and Regenerative Medicine» of NAMS of Ukraine, Kyiv, UkraineHeart Institute of the Ministry of Health of Ukraine, Kyiv, UkraineThe article describes a clinical case of a combination of myocarditis and hereditary dilated cardiomyopathy. In a 40-year-old man cardiomegaly and HF, which occurred for the first time, were initially associated with an inflammatory process in the myocardium. Further genetic examinations showed that pathological processes in the myocardium are also associated with a pathogenic mutation in the FLNC gene and a mutation in the TNT gene. The myocarditis that developed on the background of family (hereditary) dilated cardiomyopathy. However, despite the positive effect of the treatment of myocarditis and contemporary drug therapy, the progression of the pathological process in the myocardium was noted. This clinical case emphasizes the importance of a complete diagnostic examination with the use of genetic testing in certain cases. https://csic.com.ua/en/issues/archive/3-4-2023/1423-dilated-cardiomyopathy-and-myocarditis-a-clinical-case.htmldilated cardiomyopathyhereditymyocarditis |
| spellingShingle | O.V. Onyshchenko D.V. Riabenko O.A. Yepanchintseva Dilated cardiomyopathy and myocarditis: a clinical case Кардіохірургія та інтервенційна кардіологія dilated cardiomyopathy heredity myocarditis |
| title | Dilated cardiomyopathy and myocarditis: a clinical case |
| title_full | Dilated cardiomyopathy and myocarditis: a clinical case |
| title_fullStr | Dilated cardiomyopathy and myocarditis: a clinical case |
| title_full_unstemmed | Dilated cardiomyopathy and myocarditis: a clinical case |
| title_short | Dilated cardiomyopathy and myocarditis: a clinical case |
| title_sort | dilated cardiomyopathy and myocarditis a clinical case |
| topic | dilated cardiomyopathy heredity myocarditis |
| url | https://csic.com.ua/en/issues/archive/3-4-2023/1423-dilated-cardiomyopathy-and-myocarditis-a-clinical-case.html |
| work_keys_str_mv | AT ovonyshchenko dilatedcardiomyopathyandmyocarditisaclinicalcase AT dvriabenko dilatedcardiomyopathyandmyocarditisaclinicalcase AT oayepanchintseva dilatedcardiomyopathyandmyocarditisaclinicalcase |