Emergence of blaKPC-2-carrying megaplasmid in carbapenem-resistant Pseudomonas aeruginosa ST1076: Genomic and functional insights

Emergence of blaKPC-2-carrying megaplasmid in carbapenem-resistant Pseudomonas aeruginosa ST1076: Genomic and functional insights

Objective: Carbapenem-resistant Pseudomonas aeruginosa (CRPA) poses a critical challenge to clinical treatment due to its multidrug resistance and genomic plasticity. Here, we report the genomic and functional characterization of an ST1076 P. aeruginosa isolate carrying blaKPC-2 on a transferable pl...

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Bibliographic Details
Main Authors: Jing Chen, Weidong Zhu, Chen Lin, Zhen Li, Haowei Ye, Danfeng Lou
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Pseudomonas aeruginosa
ST1076
blaKPC-2
IncP-2 megaplasmid
Clonal dissemination
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716525001766
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