Overview of Preclinical and Clinical Trials of Nanoparticles for the Treatment of Brain Metastases

Overview of Preclinical and Clinical Trials of Nanoparticles for the Treatment of Brain Metastases

Brain metastases (BM), which most commonly originate from lung, breast, or skin cancers, remain a major clinical challenge, with standard treatments such as stereotactic radiosurgery (SRS), surgical resection, and whole-brain radiation therapy (WBRT). The prognosis for patients with BM remains poor,...

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Main Authors: Muhammad Izhar, Mohamed Al Gharyani, Ahed H. Kattaa, Juan J. Cardona, Ruchit P. Jain, Elaheh Shaghaghian, Yusuke S. Hori, Fred C. Lam, Deyaaldeen Abu Reesh, Sara C. Emrich, Louisa Ustrzynski, Armine Tayag, Maciej S. Lesniak, Steven D. Chang, David J. Park
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Pharmaceutics
Subjects:
nanoparticles
nanomaterials
nanocarriers
nanomedicine
nanotherapeutics
brain metastases
Online Access:https://www.mdpi.com/1999-4923/17/7/899
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