Genetically predicted smoking and body mass index mediate the relationship between insomnia and myocardial infarction

Genetically predicted smoking and body mass index mediate the relationship between insomnia and myocardial infarction

ObjectiveThis study aimed to investigate the causal relationship between insomnia and the risk of myocardial infarction (MI) and explore potential mediators such as smoking initiation, alcohol consumption and body mass index (BMI) using mendelian randomization (MR) analysis.MethodsData from 1,207,22...

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Bibliographic Details
Main Authors: Limei Deng, Yuan Gao, Dongmei Wan, Zheng Dong, Yuming Shao, Jing Gao, Wenji Zhai, Qian Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
insomnia
myocardial infarction
smoking
body mass index
alcohol consumption
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1456918/full
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https://www.frontiersin.org/articles/10.3389/fcvm.2024.1456918/full

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