Prognostic significance of microalbuminuria in non-diabetic patients with acute ischemic stroke
Microalbuminuria (MA) is nowadays recognized as an independent risk factor for ischemic stroke. In our study we investigate MA in acute ischemic stroke without diabetes and it’s correlation with severity of stroke. This is a prospective observational study done on 50 patients with non diabetic ische...
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| Format: | Article |
| Language: | English |
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Amaltea Medical Publishing House
2024-09-01
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| Series: | Romanian Journal of Neurology |
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| Online Access: | https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-04.pdf |
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| author | Jagadeswar Kakumani N. Krishna Geetha Arun Kumar B. Magesh Kumar S. |
| author_facet | Jagadeswar Kakumani N. Krishna Geetha Arun Kumar B. Magesh Kumar S. |
| author_sort | Jagadeswar Kakumani |
| collection | DOAJ |
| description | Microalbuminuria (MA) is nowadays recognized as an independent risk factor for ischemic stroke. In our study we investigate MA in acute ischemic stroke without diabetes and it’s correlation with severity of stroke. This is a prospective observational study done on 50 patients with non diabetic ischemic stroke. All the patients were subjected to a detailed history, clinical examination, biochemical and radiological investigations and assessment of the National Institutes of Health Stroke Scale (NIHSS) for grading the severity of ischemic stroke with the measurement of microalbuminuria. Cases with a mean NIHSS of 26 ± 11.418 were positive for MA, while cases with a mean NIHSS of 12.85 ± 9.06 were negative for MA, indicating that higher NIHSS were positive for MA. The relationship between MA and NIHSS was statistically significant (p <0.0001). At admission, the mean NIHSS Score for Minor stroke patients was 3.55556 ± 0.527,
while 14.3125 ± 0.4787 for moderate stroke cases, 19.0769 ± 1.605 for moderate to severe stroke, and 38.4545 ± 0.478 for severe stroke patients. The correlation between microalbuminuria and NIHHS score is 0.650, with a significant p-value
of 0.0001. MA was associated with the severity of cerebral infarction at admission and clinical outcomes 1 month after onset, and it could be used as a potential indicator of poor prognosis in patients with ischemic stroke. |
| format | Article |
| id | doaj-art-eb9804a8d4ea4544b11ee6922f1e3e73 |
| institution | Kabale University |
| issn | 1843-8148 2069-6094 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Neurology |
| spelling | doaj-art-eb9804a8d4ea4544b11ee6922f1e3e732024-12-11T08:34:36ZengAmaltea Medical Publishing HouseRomanian Journal of Neurology1843-81482069-60942024-09-0123325626010.37897/RJN.2024.3.4Prognostic significance of microalbuminuria in non-diabetic patients with acute ischemic strokeJagadeswar Kakumani0N. Krishna Geetha1Arun Kumar B.2Magesh Kumar S.3Department of General Medicine, Saveetha Medical College and Hospital, Tamilnadu, IndiaDepartment of General Medicine, Saveetha Medical College and Hospital, Tamilnadu, IndiaDepartment of General Medicine, Saveetha Medical College and Hospital, Tamilnadu, IndiaDepartment of General Medicine, Saveetha Medical College and Hospital, Tamilnadu, IndiaMicroalbuminuria (MA) is nowadays recognized as an independent risk factor for ischemic stroke. In our study we investigate MA in acute ischemic stroke without diabetes and it’s correlation with severity of stroke. This is a prospective observational study done on 50 patients with non diabetic ischemic stroke. All the patients were subjected to a detailed history, clinical examination, biochemical and radiological investigations and assessment of the National Institutes of Health Stroke Scale (NIHSS) for grading the severity of ischemic stroke with the measurement of microalbuminuria. Cases with a mean NIHSS of 26 ± 11.418 were positive for MA, while cases with a mean NIHSS of 12.85 ± 9.06 were negative for MA, indicating that higher NIHSS were positive for MA. The relationship between MA and NIHSS was statistically significant (p <0.0001). At admission, the mean NIHSS Score for Minor stroke patients was 3.55556 ± 0.527, while 14.3125 ± 0.4787 for moderate stroke cases, 19.0769 ± 1.605 for moderate to severe stroke, and 38.4545 ± 0.478 for severe stroke patients. The correlation between microalbuminuria and NIHHS score is 0.650, with a significant p-value of 0.0001. MA was associated with the severity of cerebral infarction at admission and clinical outcomes 1 month after onset, and it could be used as a potential indicator of poor prognosis in patients with ischemic stroke.https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-04.pdfmicroalbuminurianihssischemic stroke |
| spellingShingle | Jagadeswar Kakumani N. Krishna Geetha Arun Kumar B. Magesh Kumar S. Prognostic significance of microalbuminuria in non-diabetic patients with acute ischemic stroke Romanian Journal of Neurology microalbuminuria nihss ischemic stroke |
| title | Prognostic significance of microalbuminuria in non-diabetic patients with acute ischemic stroke |
| title_full | Prognostic significance of microalbuminuria in non-diabetic patients with acute ischemic stroke |
| title_fullStr | Prognostic significance of microalbuminuria in non-diabetic patients with acute ischemic stroke |
| title_full_unstemmed | Prognostic significance of microalbuminuria in non-diabetic patients with acute ischemic stroke |
| title_short | Prognostic significance of microalbuminuria in non-diabetic patients with acute ischemic stroke |
| title_sort | prognostic significance of microalbuminuria in non diabetic patients with acute ischemic stroke |
| topic | microalbuminuria nihss ischemic stroke |
| url | https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-04.pdf |
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