Indole-3-propionic acid enhances glycolytic myofiber formation in piglets through PI3K-mTOR activation and gut microbiota-driven tryptophan metabolic alteration

Indole-3-propionic acid enhances glycolytic myofiber formation in piglets through PI3K-mTOR activation and gut microbiota-driven tryptophan metabolic alteration

Indole-3-propionic acid (IPA) is a metabolite of tryptophan produced by gut bacterial catabolism that has a variety of functions, including anti-inflammatory, free radical scavenging, and regulation of glucose metabolism. The present study evaluated the effects of dietary IPA supplementation on earl...

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Bibliographic Details
Main Authors: Yezi Kong, Qi Wang, Jing Wang, Xiaoyu Qiu, Yong Yang, Jingbo Liu, Feiyun Yang, Renli Qi
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Animal Nutrition
Subjects:
Tryptophan metabolite
Skeletal muscle fiber transformation
Phosphatidylinositol 3-kinase pathway
Gut microbiome
Weaned piglet
Online Access:http://www.sciencedirect.com/science/article/pii/S2405654525000873
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