Neuroprotective Effects of Functionalized Hydrophilic Carbon Clusters: Targeted Therapy of Traumatic Brain Injury in an Open Blast Rat Model

Neuroprotective Effects of Functionalized Hydrophilic Carbon Clusters: Targeted Therapy of Traumatic Brain Injury in an Open Blast Rat Model

Traumatic brain injury (TBI) causes multiple cerebrovascular disruptions and oxidative stress. These pathological mechanisms are often accompanied by serious impairment of cerebral blood flow autoregulation and neuronal and glial degeneration. Background/Objectives: Multiple biochemical cascades are...

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Main Authors: Parasuraman Padmanabhan, Jia Lu, Kian Chye Ng, Dinesh Kumar Srinivasan, Kumar Sundramurthy, Lizanne Greer Nilewski, William K. A. Sikkema, James M. Tour, Thomas A. Kent, Balázs Gulyás, Jan Carlstedt-Duke
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Biomedicines
Subjects:
traumatic brain injury (TBI)
poly-ethylene-glycol-functionalized hydrophilic carbon clusters (PEG-HCCs)
biologically compatible carbon-based nanoclusters
open blast rat TBI model
Online Access:https://www.mdpi.com/2227-9059/12/12/2832
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