Diagnostic potential of salivary IL-1β, IL-8, SAT, S100P, and OAZ1 in oral squamous cell carcinoma, oral submucous fibrosis, and oral lichen planus based on findings from a Sri Lankan cohort

Diagnostic potential of salivary IL-1β, IL-8, SAT, S100P, and OAZ1 in oral squamous cell carcinoma, oral submucous fibrosis, and oral lichen planus based on findings from a Sri Lankan cohort

Abstract The research examined the salivary concentrations of various biomarkers, such as OAZ1, SAT, S100P, IL-1β, and IL-8 aiming to detect early-stage oral squamous cell carcinoma (OSCC). These biomarkers show potential as indicators for detecting both pre-cancerous and cancerous states within the...

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Main Authors: Kalpani Senevirathna, Thilini Anupama Nanayakkarawasam Mahakapuge, Nadeeka U. Jayawardana, Jayanthe Rajapakse, Chandrika Udumalagala Gamage, Bimalka Seneviratne, Unil Perera, Kehinde Kazeem Kanmodi, Ruwan Duminda Jayasinghe
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Salivary biomarkers
Oral cancer
mRNA
Saliva
Precancer
Online Access:https://doi.org/10.1038/s41598-024-75735-0
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https://doi.org/10.1038/s41598-024-75735-0

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