Systemic immunomodulation by irreversible electroporation versus stereotactic ablative body radiotherapy in locally advanced pancreatic cancer: the CROSSFIRE trial

Systemic immunomodulation by irreversible electroporation versus stereotactic ablative body radiotherapy in locally advanced pancreatic cancer: the CROSSFIRE trial

Background Irreversible electroporation (IRE) and stereotactic ablative body radiotherapy (SABR) are cytoreductive therapies for locally advanced pancreatic cancer (LAPC). Both may signify immunogenic cell death. We aimed to compare systemic immune responses between the treatments.Methods As part of...

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Main Authors: Danielle Vos, Anita Stam, Tanja de Gruijl, Petrousjka van den Tol, Sinead Lougheed, Joyce Bakker, Bart Geboers, Florentine Timmer, Hester Scheffer, Alette Ruarus, Laurien Vroomen, Evelien Schouten, Robbert Puijk, Frank Lagerwaard, Jan de Vries, Anna Bruynzeel, Martijn Meijerink
Format: Article
Language:English
Published: BMJ Publishing Group 2025-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/3/e010222.full
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https://jitc.bmj.com/content/13/3/e010222.full

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