SQST-1/p62-regulated SKN-1/Nrf mediates a phagocytic stress response via transcriptional activation of lyst-1/LYST.
Cells may be intrinsically fated to die to sculpt tissues during development or to maintain homeostasis. Cells can also die in response to various stressors, injury or pathological conditions. Additionally, cells of the metazoan body are often highly specialized with distinct domains that differ bot...
Saved in:
| Main Authors: | Aladin Elkhalil, Alec Whited, Piya Ghose |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-05-01
|
| Series: | PLoS Genetics |
| Online Access: | https://doi.org/10.1371/journal.pgen.1011696 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A murine model lacking Lyst recapitulates Chediak-Higashi syndrome with an earlier-onset neurodegenerative phenotype
by: Sunny Greene, et al.
Published: (2025-07-01) -
Biofilm proficient Bacillus subtilis prevents neurodegeneration in Caenorhabditis elegans Parkinson’s disease models via PMK-1/p38 MAPK and SKN-1/Nrf2 signaling
by: Marcos Francisco, et al.
Published: (2025-03-01) -
Chronic IL-1-Exposed LNCaP Cells Evolve High Basal p62-KEAP1 Complex Accumulation and NRF2/KEAP1-Dependent and -Independent Hypersensitive Nutrient Deprivation Response
by: Haley Dahl-Wilkie, et al.
Published: (2025-01-01) -
Anti-Inflammasome Effect of Impressic Acid on Diesel Exhaust Particulate Matter-Induced NLRP1 Inflammasome via the Keap1/p62/Nrf2-Signaling Pathway in Keratinocytes
by: Seung Yeon Lee, et al.
Published: (2025-05-01) -
Table of Contents Vol 62, No 1 (2020)
by: Editorial Office
Published: (2020-12-01)