KDELR1 regulates chondrosarcoma drug resistance and malignant behavior through Intergrin-Hippo-YAP1 axis

Abstract Chondrosarcoma (CS) is the second most common primary bone malignancy, known for its unique transcriptional landscape that renders most CS subtypes resistant to chemotherapy, including neoadjuvant chemotherapy commonly used in osteosarcoma (OS) treatment. Understanding the transcriptional l...

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Bibliographic Details
Main Authors: Huabin Yin, Dongjie Jiang, Yongai Li, Wenjun Chen, Jie Zhang, Xinghai Yang, Jinbo Hu, Haifeng Wei
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07264-7
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