Predictors and implications of renal injury after CD19 chimeric antigen receptor T-cell therapy

Predictors and implications of renal injury after CD19 chimeric antigen receptor T-cell therapy

Chimeric Antigen Receptor (CAR) T cells targeting CD19 induce durable remissions in patients with relapsed or refractory non-Hodgkin lymphoma (NHL), but many patients experience treatmentrelated toxicity. Cytokine release syndrome and immune effector cell-associated neurologic syndrome are extensiv...

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Main Authors: Alexander P. Boardman, Victoria Gutgarts, Jessica Flynn, Sean M. Devlin, Adam Goldman, Ana Alarcon Tomas, Joshua A. Fein, John B. Slingerland, Allison Parascondola, Richard J. Lin, Michael Scordo, Parastoo B. Dahi, Sergio Giralt, M. Lia Palomba, Gilles Salles, Karthik Nath, Moneeza Walji, Magdalena Corona, Jae H. Park, Gunjan L. Shah, Miguel-Angel Perales, Insara Jaffer-Sathick, Roni Shouval
Format: Article
Language:English
Published: Ferrata Storti Foundation 2024-11-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/11835
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https://haematologica.org/article/view/11835

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