Safety and Efficacy of Prophylactic Topical Steroid Administration for Enfortumab Vedotin–related Cutaneous Toxicity

Safety and Efficacy of Prophylactic Topical Steroid Administration for Enfortumab Vedotin–related Cutaneous Toxicity

Enfortumab vedotin (EV) is used to treat unresectable/metastatic urothelial carcinoma but often causes cutaneous toxicity (EVRCT) because of Nectin4 expression in the skin, which reduces patients’ quality of life and can lead to dose adjustments or discontinuation. We explored whether applying topic...

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Bibliographic Details
Main Authors: Yuki Kita, Takashi Nomura, Saeko Nakajima, Satoru Yonekura, Kaoru Murakami, Takayuki Sumiyoshi, Kimihiko Masui, Takayuki Goto, Ryoichi Saito, Kenji Kabashima, Takashi Kobayashi
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:European Urology Open Science
Subjects:
Enfortumab vedotin
Cutaneous toxicity
Prophylactic topical steroid
Online Access:http://www.sciencedirect.com/science/article/pii/S2666168324010863
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