Live genome imaging by CRISPR engineering: progress and problems

Abstract CRISPR–Cas-based genome imaging opened a new era of genome visualization in living cells. While genomic loci with repetitive sequences, such as centromeres and telomeres, can be reliably imaged, applying the technique to nonrepetitive genomic loci has remained challenging. Recent advancemen...

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Bibliographic Details
Main Authors: Eui-Jin Park, Hajin Kim
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01498-x
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