Antigen-specific immune therapy (CNP-106) for treatment of generalised myasthenia gravis: rationale and design of first-in-human randomised controlled trial

Introduction Myasthenia gravis (MG) is a T cell-dependent B cell-mediated autoimmune disease with pathogenic antibodies directed against components of the acetylcholine receptor (AChR). Current therapies do not address the root cause of the disease (autoimmune recognition of AChR) and are associated...

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Bibliographic Details
Main Authors: Richard J Nowak, Samantha G Brew, Molly Frey, Derrick P McCarthy, Adam Elhofy
Format: Article
Language:English
Published: BMJ Publishing Group 2024-12-01
Series:BMJ Neurology Open
Online Access:https://neurologyopen.bmj.com/content/6/2/e000836.full
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