Genetic Variations of Gene Associated with Adverse Drug Reactions to Valproic Acid in Korean Epileptic Patients
The multidrug resistance protein 2 (MRP2, ABCC2) gene may determine individual susceptibility to adverse drug reactions (ADRs) in the central nervous system (CNS) by limiting brain access of antiepileptic drugs, especially valproic acid (VPA). Our objective was to investigate the effect of ABCC2 pol...
Saved in:
Main Authors: | Ji Hyun Yi, Yang-Je Cho, Won-Joo Kim, Min Goo Lee, Ji Hyun Lee |
---|---|
Format: | Article |
Language: | English |
Published: |
BioMed Central
2013-12-01
|
Series: | Genomics & Informatics |
Subjects: | |
Online Access: | http://genominfo.org/upload/pdf/gni-11-254.pdf |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A Clinical Nomogram for Predicting Substandard Serum Valproic Acid Concentrations in Chinese Patients With Epilepsy
by: Zi-Hao Duan, MS, et al.
Published: (2025-01-01) -
Valproic acid intoxication – The importance of toxicological analysis and correct management: A case report
by: André Valle de Bairros, et al.
Published: (2025-06-01) -
Apolipoprotein E genotyping variations and their influence on cognitive outcome among idiopathic generalized epileptic patients
by: Nancy El-Salhy, et al.
Published: (2024-12-01) -
Clinical and Electrophysiological Characteristics of Patients with Juvenile Absence Epilepsy in a Turkish Cohort
by: Bülent Kara, et al.
Published: (2022-12-01) -
Valproic Acid Enhances Venetoclax Efficacy in Targeting Acute Myeloid Leukemia
by: Renshi Kawakatsu, et al.
Published: (2025-01-01)