Functional role of pyruvate kinase M2 in cell cycle arrest and extracellular matrix secretion of renal tubular epithelial cell induced by transforming growth factor-β1

Objective To explore the functional role of pyruvate kinase M2(PKM 2) in cell cycle arrest and extracellular matrix secretion of renal tubular epithelial cell induced by transforming growth factor-β1(TGF-β1).Methods HK-2 cells were stimulated by TGF-β1 for establishing an in vitro model of renal tub...

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Bibliographic Details
Main Authors: Wu Hong-luan, An Ning, Chen Xiao-cui, Pang Hao-wen, Yang Chen, Liu Hua-feng
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2021-01-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails?columnId=57902018&Fpath=home&index=0
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