UBE4B promotes gastric cancer proliferation and metastasis by mediating FAT4 ubiquitination and degradation

Abstract The ubiquitin‒proteasome system (UPS), an intracellular protein degradation pathway, plays an important role in regulating tumorigenesis and development. Ubiquitination factor E4B (UBE4B/UFD2) has been shown to be associated with the development of several cancers. The aim of this study was...

Full description

Saved in:
Bibliographic Details
Main Authors: Kaini Wu, Zixiang Guo, Yunfeng Fu, Sicheng Yang, Yating Pan, Runwei Yan, Xiaodong Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07794-8
Tags: Add Tag
No Tags, Be the first to tag this record!