Retrospective OCT Analysis of Sphingosine-1-Phosphate Modulator Fingolimod in Multiple Sclerosis

Retrospective OCT Analysis of Sphingosine-1-Phosphate Modulator Fingolimod in Multiple Sclerosis

Purpose: Sphingosine-1-phosphate (S1P) plays a pivotal role in cells as a bioactive lipid mediator, with emerging evidence suggesting that it may play a role in retinal ganglion cell survival, axonal growth, retinal pigment epithelium (RPE) barrier function, and photoreceptor function. While previou...

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Main Authors: Wilson X. Wang, MD, MPhil, Helen Rossmiller, BS, Henok Getahun, BS, Aditya Santoki, BS, Dana C. Perantie, MPH, Robert T. Naismith, MD, Rajendra S. Apte, MD, PhD
Format: Article
Language:English
Published: Elsevier 2025-11-01
Series:Ophthalmology Science
Subjects:
Multiple sclerosis
OCT
Photoreceptors
RNFL
RPE
Online Access:http://www.sciencedirect.com/science/article/pii/S2666914525001915
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