The effect and mechanism of IL-37d on neutrophil recruitment in the early stage of tumor metastasis in the lungs

The effect and mechanism of IL-37d on neutrophil recruitment in the early stage of tumor metastasis in the lungs

Abstract Background Chronic inflammation plays a pivotal role in cancer progression, with tumor-associated neutrophils (TANs) actively shaping the pre-metastatic niche. Interleukin-37 (IL-37), a known immunosuppressive cytokine, is implicated in this regulation, although its precise function remains...

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Bibliographic Details
Main Authors: Yetong Guan, Chang Gao, Yan Guo, Meifang Wang, Lining Zhang
Format: Article
Language:English
Published: Springer 2024-11-01
Series:Discover Oncology
Subjects:
IL-37d
Tumor microenvironment
Pre-metastatic niche
Neutrophil infiltration
Neutrophil spontaneous migration
Online Access:https://doi.org/10.1007/s12672-024-01608-7
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https://doi.org/10.1007/s12672-024-01608-7

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