A multi-omics Mendelian randomization identifies putatively causal genes and DNA methylation sites for asthma

A multi-omics Mendelian randomization identifies putatively causal genes and DNA methylation sites for asthma

Background: Asthma is a global chronic respiratory disease with complex pathogenesis. While current therapies offer some relief, they often fall short in effectively managing symptoms and preventing exacerbations for numerous patients. Thus, understanding its mechanisms and discovering new drug targ...

Full description

Saved in:
Bibliographic Details
Main Authors: Jia Wang, MD, Jinxin Hu, MS, Dan Qin, MD, Dan Han, MD, Jiapeng Hu, MD
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:World Allergy Organization Journal
Subjects:
Asthma
Mendelian randomization
Gene expression
DNA methylation
Mediation analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455124001406
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S1939455124001406

Similar Items