PXMP2 inhibits tumor stemness and immune infiltration in hepatocellular carcinoma based on stemness risk

PXMP2 inhibits tumor stemness and immune infiltration in hepatocellular carcinoma based on stemness risk

Abstract Background Hepatocellular carcinoma (HCC) is a complex and heterogeneous disease wherein cancer stem cells (CSCs) play a pivotal role in driving tumorigenesis, metastasis, and resistance to therapy. This study sought to map the stemness landscape of HCC and identify patients who may benefit...

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Bibliographic Details
Main Authors: Dingde Ye, Jiaqing Chen, Jian Wang, Qing Ge, Xianzhong He, Jiamu Qu, Ting Fang, Runze Wang, Shuai Mao, Qiang Wang, Qingxiang Xu, Beicheng Sun
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
Hepatocellular carcinoma
Cancer stem cells
Bioinformatics
Tumor microenvironment
Immunotherapy
Online Access:https://doi.org/10.1007/s12672-025-02976-4
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https://doi.org/10.1007/s12672-025-02976-4

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