Differential predictive value of resident memory CD8+T cell subpopulations in patients with non-small-cell lung cancer treated by immunotherapy

Differential predictive value of resident memory CD8+T cell subpopulations in patients with non-small-cell lung cancer treated by immunotherapy

Background A high density of resident memory T cells (TRM) in tumors correlates with improved clinical outcomes in immunotherapy-treated patients. In most clinical studies, TRM are defined by the CD103 marker. However, it is clearly established that not all TRM express CD103, but can be defined by o...

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Main Authors: Hang Phuong Pham, Diane Damotte, Stéphanie Corgnac, Ludger Johannes, Eric Tartour, Léa Paolini, Fathia Mami-Chouaib, Karen Leroy, Pascaline Boudou-Rouquette, Helene Blons, Francois Goldwasser, Pierre Laurent-Puig, Isabelle Cremer, Milena Hasan, Thi Tran, Nadege Gruel, Laure Gibault, Elizabeth Fabre, Marie Wislez, Patrice Ravel, Valentin Quiniou, Jennifer Arrondeau, Aziza Caidi, Jean-Philippe Villemin, Jonathan Ulmer, Louis-Victorien Vieillard, Joséphine Pineau, Alain Gey, Pierre Barennes, Valentina Libri, Sebastien Mella, Sixtine De Percin, Hortense De Saint Basile
Format: Article
Language:English
Published: BMJ Publishing Group 2024-12-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/12/e009440.full
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