Age-dependent effect of environmental enrichment on the neural 3D chromatin interactome

Summary: Aging is a multifactorial biological process resulting in physiological and cellular decline. However, our understanding of age-related changes in 3D genome organization and the effect of external interventions on this process remains limited. Here, we describe alterations in the landscape...

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Main Authors: Javier Gancedo-Verdejo, Rocío G. Urdinguio, Juan Ramón Tejedor, Raúl F. Pérez, Alfonso Peñarroya, Pablo Santamarina-Ojeda, Annalisa Roberti, Jennifer M. Kefauver, Carlota Álvarez-Díaz, Mar Rodríguez-Santamaría, José Luis Trejo, Laureano Tomás-Daza, Llorenç Rovirosa, Biola M. Javierre, Agustín F. Fernández, Mario F. Fraga
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725009532
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