Prediction and analysis of tumor infiltrating lymphocytes across 28 cancers by TILScout using deep learning

Prediction and analysis of tumor infiltrating lymphocytes across 28 cancers by TILScout using deep learning

Abstract The density of tumor-infiltrating lymphocytes (TILs) serves as a valuable indicator for predicting anti-tumor responses, but its broad impact across various types of cancers remains underexplored. We introduce TILScout, a pan-cancer deep-learning approach to compute patch-level TIL scores f...

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Main Authors: Huibo Zhang, Lulu Chen, Lan Li, Yang Liu, Barnali Das, Shuang Zhai, Juan Tan, Yan Jiang, Simona Turco, Yi Yao, Dmitrij Frishman
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00866-0
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