Uncovering nesfatin-1 and irisin hormones in schizophrenia and psychosis patients: A comparative investigation
Objective: This study aims to elucidate the potential roles of the hormones nesfatin-1 and irisin in the pathophysiology of schizophrenia and psychosis. Methods: The study involved 80 participants, divided into three groups: schizophrenia (n=30), psychosis (n=20), and controls (n=30). Blood samples...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Biomarkers in Neuropsychiatry |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666144624000303 |
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| author | Erhan Dinçer Sermin Algul Oguz Ozcelik |
| author_facet | Erhan Dinçer Sermin Algul Oguz Ozcelik |
| author_sort | Erhan Dinçer |
| collection | DOAJ |
| description | Objective: This study aims to elucidate the potential roles of the hormones nesfatin-1 and irisin in the pathophysiology of schizophrenia and psychosis. Methods: The study involved 80 participants, divided into three groups: schizophrenia (n=30), psychosis (n=20), and controls (n=30). Blood samples were collected from these participants, and the levels of irisin and nesfatin-1 were measured using the ELISA method. Results: The findings revealed that nesfatin-1 levels in schizophrenia patients were significantly higher compared to those in psychosis patients and controls. Additionally, nesfatin-1 levels in psychosis patients were significantly higher than in controls. In contrast, irisin levels were significantly lower in schizophrenia patients compared to both psychosis patients and controls. Discussion: These results suggest that nesfatin-1 and irisin may have important implications for understanding and treating schizophrenia and psychosis. Further research is needed to explore the roles of these hormones in the etiology, diagnosis, and treatment of these conditions. |
| format | Article |
| id | doaj-art-e421f9825bba45ce8f1b3ff2fb8a8446 |
| institution | Kabale University |
| issn | 2666-1446 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biomarkers in Neuropsychiatry |
| spelling | doaj-art-e421f9825bba45ce8f1b3ff2fb8a84462024-12-08T06:12:37ZengElsevierBiomarkers in Neuropsychiatry2666-14462024-12-0111100112Uncovering nesfatin-1 and irisin hormones in schizophrenia and psychosis patients: A comparative investigationErhan Dinçer0Sermin Algul1Oguz Ozcelik2Van Yuzuncu Yil University, Faculty of Medicine, Department of Physiology, Van 65100, TurkeyVan Yuzuncu Yil University, Faculty of Medicine, Department of Physiology, Van 65100, Turkey; Correspondence to: Van Yuzuncu Yil University, Department of Medicine, Department of Physiology, Van, Turkey.Kastamonu University, Faculty of Medicine, Department of Physiology, Kastamonu 37200, TurkeyObjective: This study aims to elucidate the potential roles of the hormones nesfatin-1 and irisin in the pathophysiology of schizophrenia and psychosis. Methods: The study involved 80 participants, divided into three groups: schizophrenia (n=30), psychosis (n=20), and controls (n=30). Blood samples were collected from these participants, and the levels of irisin and nesfatin-1 were measured using the ELISA method. Results: The findings revealed that nesfatin-1 levels in schizophrenia patients were significantly higher compared to those in psychosis patients and controls. Additionally, nesfatin-1 levels in psychosis patients were significantly higher than in controls. In contrast, irisin levels were significantly lower in schizophrenia patients compared to both psychosis patients and controls. Discussion: These results suggest that nesfatin-1 and irisin may have important implications for understanding and treating schizophrenia and psychosis. Further research is needed to explore the roles of these hormones in the etiology, diagnosis, and treatment of these conditions.http://www.sciencedirect.com/science/article/pii/S2666144624000303IrisinNesfatin-1SchizophreniaPsychosisPsychiatric disorders |
| spellingShingle | Erhan Dinçer Sermin Algul Oguz Ozcelik Uncovering nesfatin-1 and irisin hormones in schizophrenia and psychosis patients: A comparative investigation Biomarkers in Neuropsychiatry Irisin Nesfatin-1 Schizophrenia Psychosis Psychiatric disorders |
| title | Uncovering nesfatin-1 and irisin hormones in schizophrenia and psychosis patients: A comparative investigation |
| title_full | Uncovering nesfatin-1 and irisin hormones in schizophrenia and psychosis patients: A comparative investigation |
| title_fullStr | Uncovering nesfatin-1 and irisin hormones in schizophrenia and psychosis patients: A comparative investigation |
| title_full_unstemmed | Uncovering nesfatin-1 and irisin hormones in schizophrenia and psychosis patients: A comparative investigation |
| title_short | Uncovering nesfatin-1 and irisin hormones in schizophrenia and psychosis patients: A comparative investigation |
| title_sort | uncovering nesfatin 1 and irisin hormones in schizophrenia and psychosis patients a comparative investigation |
| topic | Irisin Nesfatin-1 Schizophrenia Psychosis Psychiatric disorders |
| url | http://www.sciencedirect.com/science/article/pii/S2666144624000303 |
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