Mechanical forces inducing oxaliplatin resistance in pancreatic cancer can be targeted by autophagy inhibition

Abstract Pancreatic cancer remains one of the most lethal malignancies, with limited treatment options and poor prognosis. A common characteristic among pancreatic cancer patients is the biomechanically altered tumor microenvironment (TME), which among others is responsible for the elevated mechanic...

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Bibliographic Details
Main Authors: Maria Kalli, Fotios Mpekris, Antonia Charalambous, Christina Michael, Chrystalla Stylianou, Chrysovalantis Voutouri, Andreas G. Hadjigeorgiou, Antonia Papoui, John D. Martin, Triantafyllos Stylianopoulos
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07268-1
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