Sibling similarity can reveal key insights into genetic architecture
The use of siblings to infer the factors influencing complex traits has been a cornerstone of quantitative genetics. Here, we utilise siblings for a novel application: the inference of genetic architecture, specifically that relating to individuals with extreme trait values (e.g. in the top 1%). Inf...
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Main Authors: | Tade Souaiaia, Hei Man Wu, Clive Hoggart, Paul F O'Reilly |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2025-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/87522 |
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