Tumor analysis of BRCA carriers reveals genomic similarities although separated by time

Tumor analysis of BRCA carriers reveals genomic similarities although separated by time

Abstract Among the dominant pathogenic genes (PG) in breast cancer are BRCA1/2. Knowing whether a patient carry one of these alterations is meaningful as it affects management. A substantial question is to what extent are the genomic profile of a tumor and its characteristics affected by the germlin...

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Main Authors: Tal Falick Michaeli, Avital Granit Mizrahi, Batia Azria, Ofra Maymon, Shai Rosenberg, Jonathan Monin, Esther Braitbart Cohen, Myriam Maoz, Luna Kadiuri, Hovav Nechushtan, Amichay Meyrowitz, Tamar Peretz
Format: Article
Language:English
Published: Springer 2024-11-01
Series:Discover Oncology
Subjects:
BRCA1/2 carriers
Exome analysis
Breast cancer
Molecular signature
Second primary
Online Access:https://doi.org/10.1007/s12672-024-01577-x
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https://doi.org/10.1007/s12672-024-01577-x

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