Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway

Baoshentongluo Formula relieves podocyte injury in diabetic kidney disease through regulating mitophagy via PINK1/Parkin signaling pathway

IntroductionDiabetic kidney disease (DKD) progression is strongly associated with podocyte mitochondrial dysfunction. The clinically effective Chinese herbal Baoshentongluo formula (BSTL) has demonstrated significant proteinuria reduction in DKD patients. HPLC-ESI-MS analysis identified characterist...

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Bibliographic Details
Main Authors: Yanyu Pang, Lei Tian, Yufei Liu, Yifan Guo, Jingwen Zhao, Yutong Wang, Mengdi Wang, Wenjing Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Endocrinology
Subjects:
diabetic kidney disease
traditional Chinese medicine
podocyte
apoptosis
mitochondria
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1606326/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1606326/full

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