Novel haplotypes of genetic polymorphisms in alcohol metabolizing enzymes in Kampala, Uganda

Abstract Objective Alcohol is metabolized to acetaldehyde by alcohol dehydrogenases (ADH) and subsequently to acetate by aldehyde dehydrogenases (ALDH). Single nucleotide polymorphisms (SNPs) in ADH1B, ADH1C and ALDH2 genes lead to haplotypes encoding isozymes which influence development of alcoholi...

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Bibliographic Details
Main Authors: Rodney Okwasiimire, Rhona K. Baingana, Dennis M. Kasozi
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Research Notes
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Online Access:https://doi.org/10.1186/s13104-025-07331-y
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