Finding spatially variable ligand-receptor interactions with functional support from downstream genes
Abstract Spatial transcriptomics has emerged as a groundbreaking tool for the study of intercellular ligand-receptor interactions (LRIs) that exhibit spatial variability. To identify spatially variable LRIs with activation evidence, we present SPIDER, which constructs cell-cell interaction interface...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-62988-0 |
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