HOXD9/APOC1 axis promotes macrophage M1 polarization to exacerbate diabetic kidney disease progression through activating NF-κB signaling pathway

Abstract Background Diabetic kidney disease (DKD) is a complication caused by end-stage diabetes mellitus and usually results in glomerular podocyte injury. Exosomes are important for intercellular information exchange. However, the effect of podocyte exosomes on DKD has not been elucidated. Methods...

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Bibliographic Details
Main Authors: Ya Feng, Yalan Zhang, Fang Gao, Miaomiao Liu, Yangyan Luo
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Hereditas
Subjects:
Online Access:https://doi.org/10.1186/s41065-024-00345-9
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