Leveraging collateral sensitivity to counteract the evolution of bacteriophage resistance in bacteria

Leveraging collateral sensitivity to counteract the evolution of bacteriophage resistance in bacteria

Abstract The escalating antibiotic resistance crisis poses a major global health threat. Bacteriophage therapy offers a promising alternative for combating multidrug‐resistant infections. However, bacterial resistance to phages remains a significant hurdle. Innovative strategies are needed to overco...

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Bibliographic Details
Main Authors: Yongqi Mu, Yuqin Song, Xueru Tian, Zixuan Ding, Shigang Yao, Yi Li, Chao Wang, Dawei Wei, Waldemar Vollmer, Gang Zhang, Jie Feng
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:mLife
Subjects:
antibiotic resistance
bacteriophage (phage) cocktails
collateral sensitivity
evolution
Klebsiella pneumoniae
Online Access:https://doi.org/10.1002/mlf2.70003
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https://doi.org/10.1002/mlf2.70003

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