Beyond Muscle Weakness: Unraveling Endocrine and Metabolic Dysfunctions in Duchenne Muscular Dystrophy, a Narrative Review

Beyond Muscle Weakness: Unraveling Endocrine and Metabolic Dysfunctions in Duchenne Muscular Dystrophy, a Narrative Review

<b>Background:</b> Duchenne muscular dystrophy (DMD) is a severe X-linked neuromuscular disorder caused by mutations in the <i>DMD</i> gene, leading to progressive muscle degeneration, loss of ambulation, and multi-systemic complications. Beyond its impact on mobility, DMD is...

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Main Authors: Giuseppe Cannalire, Giacomo Biasucci, Vanessa Sambati, Tommaso Toschetti, Arianna Maria Bellani, Anna-Mariia Shulhai, Federica Casadei, Erika Rita Di Bari, Francesca Ferraboschi, Cecilia Parenti, Maria Carmela Pera, Susanna Esposito, Maria Elisabeth Street
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomedicines
Subjects:
Duchenne muscular dystrophy
growth impairment
endocrine dysfunction
metabolic alterations
osteoporosis
puberty delay
Online Access:https://www.mdpi.com/2227-9059/13/7/1613
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