Extraction of Keratin degrading enzyme from marine Actinobacteria of Nocardia sp and their antibacterial potential against oral pathogens
Nocardia sp. thrives in challenging environmental conditions, particularly in salt-rich soils and marine ecosystems. This research aims to highlight its biological characteristics and recent applications in oral treatment. The organism is known to withstand extreme temperatures and pH levels, with s...
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| Language: | English |
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Elsevier
2024-03-01
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| Series: | Oral Oncology Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S277290602400030X |
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| author | Haripriya Arun Subash K. Santhosh Kamala Kannan Sivaperumal Pitchiah |
| author_facet | Haripriya Arun Subash K. Santhosh Kamala Kannan Sivaperumal Pitchiah |
| author_sort | Haripriya Arun Subash |
| collection | DOAJ |
| description | Nocardia sp. thrives in challenging environmental conditions, particularly in salt-rich soils and marine ecosystems. This research aims to highlight its biological characteristics and recent applications in oral treatment. The organism is known to withstand extreme temperatures and pH levels, with some strains being associated with marine organisms, while others are implicated in human diseases. Additionally, it synthesizes enzymes of biotechnological importance. The bioactive compounds and enzymes derived from this marine actinobacterium not only demonstrate to its metabolic capabilities but also suggest its potential economic value. In this research, the keratin-degrading enzyme of Nocardia sp. showed the highest antimicrobial activity at a concentration level of 100 μg/ml against oral pathogens such as Streptococcus mutans, Salmonella typhi, and Klebsiella pneumoniae. |
| format | Article |
| id | doaj-art-e237fd7591e5451a9b9d16265f94e22d |
| institution | Kabale University |
| issn | 2772-9060 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral Oncology Reports |
| spelling | doaj-art-e237fd7591e5451a9b9d16265f94e22d2025-01-09T06:15:15ZengElsevierOral Oncology Reports2772-90602024-03-019100184Extraction of Keratin degrading enzyme from marine Actinobacteria of Nocardia sp and their antibacterial potential against oral pathogensHaripriya Arun Subash0K. Santhosh1Kamala Kannan2Sivaperumal Pitchiah3Saveetha Medical College and Hospital, Saveetha Nagar, Thandalam, Chennai, Tamil Nadu, 602105, IndiaMarine Biomedical Research Lab & Environmental Toxicology Unit, Cellular and Molecular Research Centre, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, 600 077, IndiaMarine Microbial Research Lab, Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, 600 077, India; Centre for Marine Research and Conservation, Saveetha Institute of Medical and Technical Sciences, Saveetha University Chennai, Tamil Nadu, 600 077, IndiaMarine Biomedical Research Lab & Environmental Toxicology Unit, Cellular and Molecular Research Centre, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, 600 077, India; Centre for Marine Research and Conservation, Saveetha Institute of Medical and Technical Sciences, Saveetha University Chennai, Tamil Nadu, 600 077, India; Corresponding author. Marine Biomedical Research Lab & Environmental Toxicology Unit, Cellular and Molecular Research Centre, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, 600 077, India.Nocardia sp. thrives in challenging environmental conditions, particularly in salt-rich soils and marine ecosystems. This research aims to highlight its biological characteristics and recent applications in oral treatment. The organism is known to withstand extreme temperatures and pH levels, with some strains being associated with marine organisms, while others are implicated in human diseases. Additionally, it synthesizes enzymes of biotechnological importance. The bioactive compounds and enzymes derived from this marine actinobacterium not only demonstrate to its metabolic capabilities but also suggest its potential economic value. In this research, the keratin-degrading enzyme of Nocardia sp. showed the highest antimicrobial activity at a concentration level of 100 μg/ml against oral pathogens such as Streptococcus mutans, Salmonella typhi, and Klebsiella pneumoniae.http://www.sciencedirect.com/science/article/pii/S277290602400030XMarine actinobacteriumEnzymeMetabolitesOral pathogenAntimicrobial activity |
| spellingShingle | Haripriya Arun Subash K. Santhosh Kamala Kannan Sivaperumal Pitchiah Extraction of Keratin degrading enzyme from marine Actinobacteria of Nocardia sp and their antibacterial potential against oral pathogens Oral Oncology Reports Marine actinobacterium Enzyme Metabolites Oral pathogen Antimicrobial activity |
| title | Extraction of Keratin degrading enzyme from marine Actinobacteria of Nocardia sp and their antibacterial potential against oral pathogens |
| title_full | Extraction of Keratin degrading enzyme from marine Actinobacteria of Nocardia sp and their antibacterial potential against oral pathogens |
| title_fullStr | Extraction of Keratin degrading enzyme from marine Actinobacteria of Nocardia sp and their antibacterial potential against oral pathogens |
| title_full_unstemmed | Extraction of Keratin degrading enzyme from marine Actinobacteria of Nocardia sp and their antibacterial potential against oral pathogens |
| title_short | Extraction of Keratin degrading enzyme from marine Actinobacteria of Nocardia sp and their antibacterial potential against oral pathogens |
| title_sort | extraction of keratin degrading enzyme from marine actinobacteria of nocardia sp and their antibacterial potential against oral pathogens |
| topic | Marine actinobacterium Enzyme Metabolites Oral pathogen Antimicrobial activity |
| url | http://www.sciencedirect.com/science/article/pii/S277290602400030X |
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