An overview of AI in Biofunctional Materials

The integration of artificial intelligence (AI) into biofunctional materials is transforming material design, synthesis, and optimization for medical applications. Machine learning and deep learning models now predict material properties (e.g., mechanical strength, degradation rate) with > 90% ac...

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Bibliographic Details
Main Author: Dazhou Li
Format: Article
Language:English
Published: ELS Publishing (ELSP) 2025-06-01
Series:Biofunctional Materials
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Online Access:https://elsp-homepage.oss-cn-hongkong.aliyuncs.compaper/journal/open/BM/2025/bm20250010.pdf
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Summary:The integration of artificial intelligence (AI) into biofunctional materials is transforming material design, synthesis, and optimization for medical applications. Machine learning and deep learning models now predict material properties (e.g., mechanical strength, degradation rate) with > 90% accuracy, dramatically reducing trial-and-error in scaffold and nanoparticle fabrication. AI-driven platforms accelerate surface functionalization strategies to enhance cell adhesion and drug loading, while generative models design stimuli-responsive hydrogels and smart polymers that mimic tissue mechanics. Case studies include rapid optimization of nanoparticle synthesis via Bayesian frameworks and the discovery of biodegradable stent materials through random forest screening. Despite remaining challenges in data quality and regulatory alignment, these advances underscore AI’s capacity to deliver high-performance, sustainable biomaterials and point toward an interdisciplinary roadmap for next-generation therapeutic solutions.
ISSN:2959-0574
2959-0582