The nonstructural protein 13 of porcine deltacoronavirus coordinates ATP-driven duplex unwinding and ATP-independent strand annealing for nucleic acid remodeling

The nonstructural protein 13 of porcine deltacoronavirus coordinates ATP-driven duplex unwinding and ATP-independent strand annealing for nucleic acid remodeling

Abstract Background Swine diarrheal death caused by intestinal coronavirus is a key problem that needs to be solved urgently in pig production. Porcine deltacoronavirus (PDCoV) is a novel enteropathogenic coronavirus that causes acute diarrhea in suckling piglets, resulting in serious economic losse...

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Bibliographic Details
Main Authors: Lihan Tao, Quanyong Zhou, Chengcheng Wu, Hongping Jiang, Jianzhen Huang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Veterinary Research
Subjects:
Porcine deltacoronavirus
NSP13
Unwinding efficiency
Strand-annealing
Antiviral drugs
Online Access:https://doi.org/10.1186/s12917-025-04851-4
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https://doi.org/10.1186/s12917-025-04851-4

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