Androgen receptor signaling induces hemorrhage and angiogenesis in the irradiated bladder

Abstract The underlying mechanism of radiation cystitis remains unknown, however, angiogenesis induced by hypoxia seems to be important because hyperbaric oxygen therapy which suppresses HIF-1 is clinically effective and significantly associated with androgen receptor signaling. We herein assessed t...

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Bibliographic Details
Main Authors: Takahiro Komori, Hiroki Ide, Junichi Fukada, Yuto Baba, Kazuhiro Matsumoto, Hiroshi Miyamoto, Mototsugu Oya
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-15245-9
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